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Eric Dane's cause of death confirmed 1 week after his death

The “Grey’s Anatomy” star died almost a year after he announced his amyotrophic lateral sclerosis (ALS) diagnosis.

Eric Dane’s cause of death confirmed 1 week after his death

The "Grey's Anatomy" star died almost a year after he announced his amyotrophic lateral sclerosis (ALS) diagnosis.

By Mekishana Pierre

Mekishana Pierre author photo

Mekishana Pierre

Mekishana Pierre is a news writer at **. She has been working at EW since 2025. Her work has previously appeared on *Entertainment Tonight* and Popsugar.

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March 2, 2026 1:58 p.m. ET

Actor Eric Dane has been diagnosed with ALS, He is photographed at the St. Regis in Washington, DC on September 30, 2025.

Eric Dane photographed at the St. Regis in Washington, D.C., on Sept. 30, 2025. Credit:

Marvin Joseph/The Washington Post via Getty

Eric Dane's cause of death has been confirmed a little over a week after his family shared the news of his death.

The actor — best known for his role as Dr. Mark Sloan (a.k.a. McSteamy) on *Grey’s Anatomy* and later for costarring on HBO's *Euphoria* — died of respiratory failure, according to PEOPLE. The outlet reported that Dane's death certificate listed amyotrophic lateral sclerosis (ALS) as an underlying cause of death.

Dane revealed he had been diagnosed with ALS, also known as Lou Gehrig's disease, in April 2025, a progressive and fatal nervous system disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control; therefore, it affects patients’ ability to breathe, speak, and move, according to the Mayo Clinic. There is no cure, though some patients can live for decades.

After sharing his diagnosis, Dane became the face of a public campaign to find federal funding for research on the incurable neurological disease. In September, a noticeably less mobile Dane joined doctors and representatives from the I Am ALS organization for a discussion with California Congressman Eric Swalwell about investing in innovative treatments to ensure access to quality care for those diagnosed with ALS, as well as their families and researchers.

*This story is still developing.*

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